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[modeller_usage] Re: To Model missing domains in the content of the rest
- To: modeller_usage@listsrv.ucsf.edu
- Subject: [modeller_usage] Re: To Model missing domains in the content of the rest
- From: Shirley Li <li19104 AT yahoo.com>
- Date: Thu, 8 Dec 2005 13:15:23 -0800 (PST)
Dear MODELLER experts,
I have a target protein, whose X-ray structure is PARTIALLY available (the middle part, named domain B). There are two big regions missing (domain A & C) in the crystal structure, with more than 50 residues in each I would like to use MODELLER to model domain A & C, and there are templates available. I wonder if it is possible to include THE CONTENT OF domain B. in another word, to create a complete model of A-B-C while keep the coordinates of B domain fixed.
Any help/information will be greatly appreciated.
Shirley
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