Re: [modeller_usage] What's the difference of "refinement level" in MD

[Modeller Caretaker <>]

Yun He wrote:
> As subject, how much difference does the FAST or SLOW refinement level effect 
> the final models in MD? Does it really worth for a loooong computation to 
> build a more accurate model?

They change the amount of simulated annealing done (number of steps at 
each temperature, and number of temperatures to use). It's probably only 
worth using slower refinement levels when you have larger models, but 
you should try them and see for yourself.

	Ben Webb, Modeller Caretaker
--
             http://www.salilab.org/modeller/
Modeller mail list: http://salilab.org/mailman/listinfo/modeller_usage