Hello All,
I want to model a multi-domain protein. Thus, I aligned manually all
templates (corresponding to the individual domains) and used them as an
input for Modeller. (Note that the templates overlap only over few
residues.)
However, when I compared the initial model (.ini) to the aligned
templates, I saw that Modeller did something more than just transferring
the coordinates from the templates. Namely, the relative orientation of
domains is not as in my structural alignment. Is thee any way to force
Modeller to use exactly the input coordinates?
initial_malign3d is set to False
and default transfer_xyz() is used
Thanks for help!
Staszek