Re: [modeller_usage] Can I calculate the "Objective Function" based on a PDB without doing the comparative modelling?

[Modeller Caretaker <>]

On 6/13/20 7:08 PM, ZHANG Cheng via modeller_usage wrote:
> Now I have a structure generated by RosettaCM, and I want to use the 
> MODELLER's "Objective Function" to evaluate its reliability. Would it be 
> possible?

The objective function scores how well the model fits the set of 
Modeller restraints. It wouldn't tell you anything useful for a model 
built using another technique. It sounds like what you're looking for is 
a model evaluation method, such as DOPE:
https://salilab.org/modeller/9.24/manual/node259.html
or SOAP:
https://salilab.org/modeller/9.24/manual/node283.html

There's also a web server at https://salilab.org/evaluation/

	Ben Webb, Modeller Caretaker
--
             https://salilab.org/modeller/
Modeller mail list: https://salilab.org/mailman/listinfo/modeller_usage