[modeller_usage] Re: Making a heterotetramer model, while one of the chain is built by using two template

[Modeller Caretaker <modeller-care@ucsf.edu>]

On 11/3/23 1:45 AM, rpw641--- via modeller_usage wrote:
> As the Subject said, I want to make a heterotetramer model, and make
> one of the chains by using two template. I know how to make
> heterotetramer model or build a single chain with multitemplate. The
> problem is that I don't know how to combine these two in my case.

This wouldn't be substantially different from the single chain case - 
you would just need to align each template with the right part of the 
model sequence. If you have a 4-chain template and you want to use a 
second template for part of one chain, your alignment would look 
something like


temp1    AAAA/BBBB/CCCC/DDDD*
temp2    ----/----/CCCC/----*
model    AAAA/BBBB/CCCC/DDDD*


	Ben Webb, Modeller Caretaker
-- 
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