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[modeller_usage] How to generate Homology models using a computer farm
- To: modeller_usage@listsrv.ucsf.edu
- Subject: [modeller_usage] How to generate Homology models using a computer farm
- From: Caio Veloso <caju AT uai.com.br>
- Date: Mon, 10 May 2010 17:19:16 -0300
- Posted-date: Mon, 10 May 2010 17:19:14 -0300
Dear All,
In order to build several models of a target protein, we are running
the same Python script on different computers at the same time.
In this case, the script is the same and the proteins used as models
are also the same.
At the first attempt we expected to build different models and then
assess them, and choose the
best one or change your alignment/template if none of the models are
acceptable.
However when these models were evaluated, we discovered that MODELLER
has built
the same models, in the same order on all computers.
I want know whether exist some parameters that could be adjusted at the
Python script,
(a kind of random number generator ?) in order to assure that different
sets of models
will be generate on each computer?
Regards,
Caio Veloso