Re: [modeller_usage] How to generate Homology models using a computer farm

[Modeller Caretaker <modeller-care@ucsf.edu>]

On 5/10/10 1:19 PM, Caio Veloso wrote:
> In order to build several models of a target protein, we are running
> the same Python script on different computers at the same time.
...
> we discovered that MODELLER has built the same models, in the same
> order on all computers.

Indeed, because Modeller is deterministic, and gives reproducable results.

> I want know whether exist some parameters that could be adjusted at
> the Python script, (a kind of random number generator ?) in order to
> assure that different sets of models will be generate on each
> computer?

You need to set rand_seed to a different value on each machine -
something like -2 - (number of machine) should do the trick:
http://salilab.org/modeller/9v8/manual/node110.html

	Ben Webb, Modeller Caretaker
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