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Andrej Sali

Professor

Steve Ha

Ignacia Echeverria

Postdoctoral Scholar

• Structural modeling and analysis of pathogen-host complexes using integrative techniques.

Kala Bharath Pilla

Postdoctoral Scholar

• Develop a framework for computing a meta-model of the cell.
• Protein structure determination by experimental and computational hybrid approach.

Tanmoy Sanyal

Postdoctoral Scholar

• Transport through the Nuclear Pore Complex.
• Development of meta-modeling frameworks for insulin pathways in the pancreatic-beta cell.

Jeremy Tempkin

Postdoctoral Scholar

• Modeling the assembly of the nuclear pore complex
• Development of spatiotemporal integrative modeling methods

Sai Ganesan

Postdoctoral Scholar

• Determining the structure(s) of SWI/SNF protein complex by integrating EM and proteomics data
• Predicting prokaryotic metabolic pathways and networks by integrating structural, evolutionary and functional information
• Integrating pathway and structure prediction for metabolons

Nikita Chopra

Postdoctoral Scholar

• Discovery of small-molecule activators of human proteasome.
• Structural modeling of mammalian target of rapamycin (mTORC2) using integrative modeling techniques.

Rakesh Ramachandran

Postdoctoral Scholar

• Modeling of macromolecular assemblies using evolutionary restraints
• Understanding conformational landscape of macromolecular assemblies guided by electron microscopy data

Barak Raveh

Postdoctoral Scholar

• My aim is to create a data-driven model of nucelocytoplasmic transport through the Nuclear Pore Complex, based on multiple sources of experimental data.

Daniel Saltzberg

Postdoctoral Scholar

• Structural modelling of intermediate states in the aggregation pathway of Abeta using integrative techniques.
• Development and implementation of structural restraints for hydrogen-deuterium exchange data.

Shruthi Viswanath

Postdoctoral Scholar

• Determining the structure of the spindle pole body (SPB) complex by integrative modeling using data from crystallography, SAXS, cryo-EM, ET, FRET and proteomics experiments

Seth Axen

Graduate Student

Graduate Program in Biological and Medical Informatics

• Integrative modeling of protein ensembles and dynamics

Ilan Chemmama

Graduate Student

Graduate Program in Biophysics

• Integration of various sources of data for characterizing ensemble of states.
• Mapping of energy landscape from ensemble of states.

Ben Webb

Academic Coordinator

• Development of the Modeller package for comparative modeling.
• Development of the IMP platform for assemblies and modeling.
• Refinement of protein structure models.
• Systems administration.